abstract：:Prior studies have suggested that the antifibrinolytic drug aprotinin increases the infarct size after ischemia and reperfusion (I/R) and attenuates the effect of ischemic preconditioning (IPC). Aprotinin was replaced by tranexamic acid (TXA) in clinical practice. Here, we investigated whether TXA influences I/R injur...

journal_title：Anesthesia and analgesia

authors： van Caster P,Eiling S,Boekholt Y,Behmenburg F,Dorsch M,Heinen A,Hollmann MW,Huhn R

更新日期：2018-02-01 00:00:00

abstract：:Inferential statistics relies heavily on the central limit theorem and the related law of large numbers. According to the central limit theorem, regardless of the distribution of the source population, a sample estimate of that population will have a normal distribution, but only if the sample is large enough. The rel...

journal_title：Anesthesia and analgesia

authors： Mascha EJ,Vetter TR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Landmark and ultrasound-guided transversus abdominis plane blocks have demonstrated an opioid-sparing effect postoperatively after cesarean delivery. The more posterior quadratus lumborum (QL) might provide superior local anesthetic spread to the thoracolumbar fascia and paravertebral space. The aim of our s...

journal_title：Anesthesia and analgesia

authors： Krohg A,Ullensvang K,Rosseland LA,Langesæter E,Sauter AR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Lung-protective ventilation (LPV) has been demonstrated to improve clinical outcomes in surgical patients. There are very limited data on the current use of LPV for patients undergoing 1-lung ventilation (1LV) despite evidence that 1LV may be a particularly important setting for its use. In this multicenter ...

journal_title：Anesthesia and analgesia

authors： Colquhoun DA,Naik BI,Durieux ME,Shanks AM,Kheterpal S,Bender SP,Blank RS,MPOG Investigators.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Statistical heterogeneity can increase the uncertainty of results and reduce the quality of evidence derived from systematic reviews. At present, it is uncertain what the major factors are that account for heterogeneity in meta-analyses of analgesic adjuncts. Therefore, the aim of this review was to identify...

journal_title：Anesthesia and analgesia

authors： Doleman B,Sutton AJ,Sherwin M,Lund JN,Williams JP

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Rates of hypothermia for women undergoing spinal anesthesia for cesarean delivery are high and prevention is desirable. This trial compared the effectiveness of preoperative warming versus usual care among women receiving intrathecal morphine, which is thought to exacerbate perioperative heat loss. METHODS:...

journal_title：Anesthesia and analgesia

authors： Munday J,Osborne S,Yates P,Sturgess D,Jones L,Gosden E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Perineural dexamethasone has gained popularity in regional anesthesia to prolong analgesia duration. However, uncertainty remains regarding the optimal perineural dose. Clarification of this characteristic is of significant importance as the administration of dexamethasone may lead to dose-dependent complica...

journal_title：Anesthesia and analgesia

authors： Kirkham KR,Jacot-Guillarmod A,Albrecht E

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies and transfusion guidelines remain a heavily debated clinical topic. Previous investigational trials have shown that acute isovolemic hemodilution does not limit adequate oxygen delivery; however, a true critical hemoglobin level has never been investigated or defined due to safe...

journal_title：Anesthesia and analgesia

authors： Sims CR 3rd,Delima LR,Calimaran A,Hester R,Pruett WA

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The perioperative assessment of right ventricular (RV) function remains a challenge. Tricuspid annular plane systolic excursion (TAPSE) using M-mode is a widely used measure of RV function. However, accurate alignment of the ultrasound beam with the direction of annular movement can be difficult with transes...

journal_title：Anesthesia and analgesia

authors： Shen T,Picard MH,Hua L,Burns SM,Andrawes MN

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Anesthesia information management systems (AIMSs) have been effectively used to improve quality in anesthesia care, and have enabled the development of mandatory quality assurance (QA) reporting systems for adverse events (AEs). While this approach has been shown to increase event reporting over time, the lo...

journal_title：Anesthesia and analgesia

authors： Wanderer JP,Gratch DM,Jacques PS,Rodriquez LI,Epstein RH

更新日期：2018-01-01 00:00:00

abstract：:Neuraxial anesthesia may improve perioperative outcomes when compared to general anesthesia; however, this is controversial. We performed a systematic review and meta-analysis using randomized controlled trials and population-based observational studies identified in MEDLINE, PubMed, and EMBASE from 2010 to May 31, 20...

journal_title：Anesthesia and analgesia

authors： Smith LM,Cozowicz C,Uda Y,Memtsoudis SG,Barrington MJ

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the ...

journal_title：Anesthesia and analgesia

authors： Segal S,Pancaro C,Bonney I,Marchand JE

更新日期：2017-12-01 00:00:00

abstract：:Descriptive statistics are specific methods basically used to calculate, describe, and summarize collected research data in a logical, meaningful, and efficient way. Descriptive statistics are reported numerically in the manuscript text and/or in its tables, or graphically in its figures. This basic statistical tutori...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The diagnosis of myocardial infarction (MI) after noncardiac surgery has traditionally relied on using relatively insensitive contemporary cardiac troponin (cTn) assays. We hypothesized that using a recently introduced novel high-sensitivity cTnT (hscTnT) assay would increase the detection rate of perioperat...

journal_title：Anesthesia and analgesia

authors： Brown JC,Samaha E,Rao S,Helwani MA,Duma A,Brown F,Gage BF,Miller JP,Jaffe AS,Apple FS,Scott MG,Nagele P

更新日期：2017-11-01 00:00:00

abstract：:While a large number of studies has examined the efficacy of opioid-sparing analgesics in adult surgical populations, fewer studies are available to guide postoperative pain treatment in pediatric patients. We systematically reviewed available publications on the use of systemic nonopioid agents for postoperative anal...

journal_title：Anesthesia and analgesia

authors： Zhu A,Benzon HA,Anderson TA

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Opioids are frequently used in chronic pain management but are associated with significant morbidity and mortality in some patient populations. An important avenue for identifying complications-including serious or rare complications-is the study of closed malpractice claims. The present study is intended to...

journal_title：Anesthesia and analgesia

authors： Abrecht CR,Brovman EY,Greenberg P,Song E,Rathmell JP,Urman RD

更新日期：2017-11-01 00:00:00

abstract：:Several federal agencies have recently noted that the United States is in the midst of an unprecedented "opioid epidemic," with an increasing number of opioid-related overdoses and deaths. Providers currently face 3 population-level, public health challenges in providing optimal perioperative pain care: (1) the contin...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Kain ZN

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which ...

journal_title：Anesthesia and analgesia

authors： Muffly MK,Chen MI,Claure RE,Drover DR,Efron B,Fitch WL,Hammer GB

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) ...

journal_title：Anesthesia and analgesia

authors： Efrati S,Bolotin G,Levi L,Zaaroor M,Guralnik L,Weksler N,Levinger U,Soroksky A,Denman WT,Gurman GM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Admission hypocalcemia predicts both massive transfusion and mortality in severely injured patients. However, the effect of calcium derangements during resuscitation remains unexplored. We hypothesize that any hypocalcemia or hypercalcemia (either primary or from overcorrection) in the first 24 hours after s...

journal_title：Anesthesia and analgesia

authors： MacKay EJ,Stubna MD,Holena DN,Reilly PM,Seamon MJ,Smith BP,Kaplan LJ,Cannon JW

更新日期：2017-09-01 00:00:00

abstract：:With the recent rapid adoption of electronic medical records (EMRs), studies reporting results based on EMR data have become increasingly common. While analyzing data extracted from our EMR for a retrospective study, we identified various types of erroneous data entries. This report investigates the root causes of the...

journal_title：Anesthesia and analgesia

authors： Baier AW,Snyder DJ,Leahy IC,Patak LS,Brustowicz RM

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:Serious complications are common during the intensive care of postoperative cardiac surgery patients. Some of these complications may be influenced by communication during the process of handover of care from the operating room to the intensive care unit (ICU) team. A structured transfer of care process ma...

journal_title：Anesthesia and analgesia

authors： Hall M,Robertson J,Merkel M,Aziz M,Hutchens M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:In cardiac surgery, pulmonary hypertension is an important prognostic factor for which several treatments have been suggested over time. In this systematic review and meta-analysis, we compared the efficacy of inhaled aerosolized vasodilators to intravenously administered agents and to placebo in the treatme...

journal_title：Anesthesia and analgesia

authors： Elmi-Sarabi M,Deschamps A,Delisle S,Ased H,Haddad F,Lamarche Y,Perrault LP,Lambert J,Turgeon AF,Denault AY

更新日期：2017-08-01 00:00:00

abstract：:Implanted electronic medical devices. or stimulators such as pacemakers and nerve stimulators have grown enormously in diversity and complexity over recent decades. The function and potential interaction of these devices with the perioperative environment is of increasing concern for anesthesiologists and surgeons. Be...

journal_title：Anesthesia and analgesia

authors： Srejic U,Larson P,Bickler PE

更新日期：2017-07-01 00:00:00

abstract：:Minimally invasive fetoscopic surgery for spina bifida aperta is a new therapeutic approach to preserve neurologic function by protecting exposed neural tissue. The anesthetic management is of paramount importance for the success of the procedure. Therefore, our protocol was developed with particular attention to safe...

journal_title：Anesthesia and analgesia

authors： Arens C,Koch C,Veit M,Greenberg RS,Lichtenstern C,Weigand MA,Khaleeva A,Schuerg R,Kohl T

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:The effect of interscalene block (ISB) on pulmonary function of obese participants has not been investigated. The goal of this study is to assess the association of obesity (body mass index [BMI] >29 kg/m vs BMI <25 kg/m) and change in forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV...

journal_title：Anesthesia and analgesia

authors： Melton MS,Monroe HE,Qi W,Lewis SL,Nielsen KC,Klein SM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：:Part I of this review discussed the similarities between embryogenesis, mammalian adaptions to hypoxia (primarily driven by hypoxia-inducible factor-1 [HIF-1]), ischemia-reperfusion injury (and its relationship with reactive oxygen species), hibernation, diving animals, cancer, and sepsis, and it focused on the common...

journal_title：Anesthesia and analgesia

authors： Thiele RH

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Increasing costs of material resources challenge hospitals to stay profitable. Particularly in anesthesia departments and intensive care units, bronchoscopes are used for various indications. Inefficient management of single- and multiple-use systems can influence the hospitals' material costs substantially....

journal_title：Anesthesia and analgesia

authors： Edenharter GM,Gartner D,Pförringer D

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:In children, postoperative respiratory rate (RR) monitoring by transthoracic impedance (TI), capnography, and manual counting has limitations. The rainbow acoustic monitor (RAM) measures continuous RR noninvasively by a different methodology. Our primary aim was to compare the degree of agreement and accurac...

journal_title：Anesthesia and analgesia

authors： Patino M,Kalin M,Griffin A,Minhajuddin A,Ding L,Williams T,Ishman S,Mahmoud M,Kurth CD,Szmuk P

更新日期：2017-06-01 00:00:00

abstract：:As of November 2016, the Florida Department of Health (FDH) and the Centers for Disease Control and Prevention have confirmed more than 4000 travel-related Zika virus (ZIKV) infections in the United States with >700 of those in Florida. There have been 139 cases of locally acquired infection, all occurring in Miami, F...

journal_title：Anesthesia and analgesia

authors： Tutiven JL,Pruden BT,Banks JS,Stevenson M,Birnbach DJ

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The Perioperative Surgical Home (PSH) seeks to remedy the currently highly fragmented and expensive perioperative care in the United States. The 2 specific aims of this health services research study were to assess the association between the preoperative and postoperative elements of an initial PSH model an...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Barman J,Hunter JM Jr,Jones KA,Pittet JF

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:A predictive model that can identify patients who are at an increased risk for prolonged postanesthesia care unit (PACU) stay could help optimize resource utilization and case sequencing. Although previous studies identified some predictors, there is not a model that only utilizes various patients demographi...

journal_title：Anesthesia and analgesia

authors： Gabriel RA,Waterman RS,Kim J,Ohno-Machado L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Transesophageal echocardiography (TEE) is a valuable monitor for patients undergoing cardiac and noncardiac surgery as it allows for evaluation of cardiovascular compromise in the perioperative period. It is challenging for anesthesiology residents and medical students to learn to use and interpret TEE in th...

journal_title：Anesthesia and analgesia

authors： Kleiman AM,Forkin KT,Bechtel AJ,Collins SR,Ma JZ,Nemergut EC,Huffmyer JL

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral ultrasound-guided TAP block with single...

journal_title：Anesthesia and analgesia

authors： Tawfik MM,Mohamed YM,Elbadrawi RE,Abdelkhalek M,Mogahed MM,Ezz HM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Inhalation agents are being used in place of intravenous agents to provide sedation in some intensive care units. We performed a systematic review and meta-analysis of prospective randomized controlled trials, which compared the use of volatile agents versus intravenous midazolam or propofol in critical care...

journal_title：Anesthesia and analgesia

authors： Jerath A,Panckhurst J,Parotto M,Lightfoot N,Wasowicz M,Ferguson ND,Steel A,Beattie WS

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The presence of an endotracheal tube is the main cause for developing ventilator-associated pneumonia (VAP), but pneumonia can still develop in hospitalized patients after endotracheal tube removal (postextubation pneumonia [PEP]). We hypothesized that short-term intubation (24 hours) can play a role in the ...

journal_title：Anesthesia and analgesia

authors： Rezoagli E,Zanella A,Cressoni M,De Marchi L,Kolobow T,Berra L

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:It remains unknown whether continuous or scheduled intermittent bolus local anesthetic administration is preferable for transversus abdominis plane (TAP) catheters. We therefore tested the hypothesis that when using TAP catheters, providing local anesthetic in repeated bolus doses increases the cephalad-caud...

journal_title：Anesthesia and analgesia

authors： Khatibi B,Said ET,Sztain JF,Monahan AM,Gabriel RA,Furnish TJ,Tran JT,Donohue MC,Ilfeld BM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:We have shown previously that either echocardiographic indices of diastolic dysfunction or increased preoperative brain natriuretic peptide (BNP) predict postoperative atrial fibrillation (POAF). Because these 2 predictors of POAF have not been evaluated together, our goal was to further elucidate their conc...

journal_title：Anesthesia and analgesia

authors： Brecher O,Gulati H,Roistacher N,Zhang H,Shi W,Thaler HT,Amar D

更新日期：2017-04-01 00:00:00

abstract：:The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership with the US Food and Drug Administration, convened a meeting of sedation e...

journal_title：Anesthesia and analgesia

authors： Williams MR,Ward DS,Carlson D,Cravero J,Dexter F,Lightdale JR,Mason KP,Miner J,Vargo JJ,Berkenbosch JW,Clark RM,Constant I,Dionne R,Dworkin RH,Gozal D,Grayzel D,Irwin MG,Lerman J,O'Connor RE,Pandharipande P,Rappap

更新日期：2017-03-01 00:00:00